Presented by: Andreas Hugi, IRSweep
Understanding the mechanism of a chemical reaction is an important step away from trial-and-error-based reaction optimization. By studying the structures of intermediates — how long they exist and the ways in which they can and cannot react — reactions can be intelligently designed and controlled. Infrared absorption is a prime choice for such reaction monitoring tasks due to its sensitivity and specificity. However, the achievable speed is often limited by the available instrumentation.
Dual-comb spectroscopy (DCS) based on quantum cascade laser (QCL) frequency combs has become a major contender in application spaces previously dominated by Fourier transform infrared (FTIR) spectrometers. QCL DCS has led to a paradigm shift in applications that previously relied on step-scan techniques, such as protein dynamic analysis and spectroelectrochemistry.
In this presentation, Hugi focuses on the high signal-to-noise ratios that can be achieved at millisecond timescales, without experiment repetition, using dual-comb spectroscopy based on QCLs. Continuous reaction monitoring with 220 spectra/s can be achieved with a high spectral resolution >0.3 cm-1. Pushing the DCS technique, Hugi and colleagues manage to get sub-µs time resolution for up to 128 ms acquisition time. Furthermore, the team has improved the spectral coverage of QCL DCS covering >100 cm-1. The IRis-F1 combines all these features in a single instrument, resulting in versatility that paves the way to the next-generation mid-infrared spectroscopy instrumentation.
About the presenter
Andreas Hugi, Ph.D., is a founder of IRsweep. IRsweep's vision is to revolutionize optical sensing by introducing an ultrafast laser spectrometer in the mid-infrared. It is based on Quantum Cascade Laser (QCL) Frequency Combs invented by IRsweep's co-founders in 2012 at ETH Zurich. Prior to co-founding IRsweep, Andreas received his PhD on single-mode and comb operation of broadband QCLs in 2013 under the supervision of Jérôme Faist at ETH Zurich. He received his Master of Science in Micro- and Nanotechnology in 2007 from the University of Neuchâtel. Andreas was awarded the ETH Medal for an outstanding doctoral thesis and the Omega student award for his master thesis.
About the sponsor(s)
- Wavelength Electronics Inc. - Wavelength's low-noise QCL controller enables narrow linewidth and stable center wavelength for lowered detection thresholds in Mid-IR gas sensing systems.